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作者在174507无癌症者中进行队列研究,企图阐明铁储存和癌症危险性之间的关系。根据第1次健康检查时记录的近期内有无使用过铁剂或其他抗贫血治疗以及Hb水平和总铁结合力(TIBC)作为铁储存多少的间接指标,将调查对象按性别分成“使用铁剂者”和“未使用铁剂者”两组进行随访。并记录吸烟情况作为混杂因素做统计学处理。其中有15%妇女和<4%的男子接受过铁剂治疗,从使用铁剂到诊断癌症平均随访8.3年(2.1-16年),从测定TIBC到诊断癌症平均6.6年(2.1-11.4年)。使用铁剂者Hb水平低于未使用者,女性使用铁剂者TIBC水平
The authors conducted a cohort study of 174507 cancer-free individuals in an attempt to elucidate the relationship between iron storage and cancer risk. According to the first medical examination recorded in the near future whether the use of iron or other anti-anemia treatment and Hb levels and total iron binding capacity (TIBC) as an indirect indicator of the amount of iron storage, the survey by sex into “use of iron Dose ”and“ no use of iron ”two groups were followed up. And record smoking as a confounding factor to do statistical analysis. Of these, 15% of women and <4% of men received iron treatment, with an average follow-up of 8.3 years (2.1 to 16 years) from iron use to diagnosis of cancer, an average of 6.6 years (2.1 to 1.4 years) . Hb levels were lower in those who used iron than those who did not, and women who used iron supplements had TIBC levels