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目的了解孕妇对无创产前筛查(NIPT)的认知现状及支付意愿情况。方法 2015年9-10月,采用自行设计的孕妇支付意愿调查表调查某省3家高通量基因测序技术临床应用试点单位的743例孕妇,调查内容包括:孕妇基本人口学特征、对NIPT的认知和支付意愿情况。结果本次现场调查共发放孕妇支付意愿调查表800份,回收743份,回收有效率92.88%。孕妇对NIPT的认知程度不高,获取信息的渠道主要是医务人员的介绍,但大多数孕妇表达了在孕早期愿意多了解相关筛查与诊断的方法。孕妇对NIPT产前筛查愿意支付的费用平均数为1 483.12元,且孕妇的支付意愿水平与年龄和收入有关。结论有必要有针对性地给予孕妇以系统的理论知识指导,提高孕妇对产前筛查知识掌握的水平,对产前筛查技术尤其是NIPT新技术的临床应用及推广有重要意义。
Objective To understand the status quo of pregnant women on non-invasive prenatal screening (NIPT) awareness and willingness to pay. Methods From September to October 2015, 743 pregnant women in clinical application pilot units of 3 high-throughput gene sequencing technologies in a province were surveyed by using self-designed questionnaire of willingness to pay for pregnant women. The survey included the basic demographic characteristics of pregnant women, Cognition and willingness to pay. Results A total of 800 survey questionnaires about the willingness to pay for pregnant women were distributed in this field survey, with a total of 743 samples collected. The recovery efficiency was 92.88%. Pregnant women have a low level of cognition of NIPT. Most of the channels for obtaining information are introduction of medical personnel, but most pregnant women express their willingness to know more about screening and diagnosis in early pregnancy. The average number of pregnant women who are willing to pay for prenatal screening of NIPT is 1 483.12 yuan, and the level of willingness of pregnant women to pay is related to their age and income. Conclusion It is necessary to give targeted guidance to pregnant women with systematic theoretical knowledge to improve the level of knowledge of pregnant women on prenatal screening, which is important for the clinical application and promotion of new prenatal screening techniques, especially NIPT.