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内胚窦瘤来源于原始生殖细胞或多源性胚胎细胞,常发生于卵巢、睾丸。本文共收集4例卵巢内胚窦瘤,并就其病理特征和临床治疗方面进行讨论。其病理组织形态包括5种基本结构特征,(1)疏松的空网状结构;(2)实体结构;(3)特征性的血管周围结构;(4)多囊性的卵黄结构;(5)透明小体结构。好发于幼女和青年妇女,平均年龄16.5～19岁,死亡率极高,手术治疗配合化疗可提高存活率。
Endodermal sinus tumors originate from primordial germ cells or multiple embryonic cells, often occurring in the ovary and testis. This article collected a total of 4 cases of ovarian endodermal sinus tumors, and discussed its pathological features and clinical treatment. The histopathology consists of five basic structural features, (1) loose empty reticular formation, (2) solid structure, (3) characteristic perivascular structure, (4) polycystic yolk structure, (5) Transparent body structure. Occur in young girls and young women, the average age of 16.5 to 19 years old, the mortality rate is very high, surgical treatment with chemotherapy can improve the survival rate.