在美国卵巢癌的死亡率占癌的第四位,虽然卵巢癌的发病率只占妇女癌症的5%,但却是最常见的死亡原因。在美国每年约有14,000例晚期卵巢癌,而且发病率还在增加。单一药物的化疗治疗卵巢癌已取得一些令人满意的效果。烷化剂(环磷酰氨、噻替 In the United States, the mortality rate of ovarian cancer is the fourth most common cancer. Although the incidence of ovarian cancer is only 5% of cancers in women, it is the most common cause of death. In the United States, there are approximately 14,000 cases of advanced ovarian cancer each year, and the incidence is still increasing. Single-agent chemotherapy for ovarian cancer has achieved some satisfactory results. Alkylating agents (cyclophosphamide, thiophene