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用单克隆抗体（ＯＫＴ３，ＯＫＴ４，ＯＫＴ８，ＯＫＴ１１）检测肺癌胸水１７例和结核性胸膜炎１７例胸水中的淋巴细胞表型。结果：结核组淋巴细胞绝对数高于癌性胸水。结构组Ｔ３＋，Ｔ４＋，Ｔ１１＋的百分数和绝对数均高于癌性胸水，有显著差异，结核组Ｔ８＋绝对数高于肺癌组，百分数低于肺癌组。肺癌及结核性胸水中的淋巴细胞均可被ＩＬ－２激活为ＥＡＬ，可杀伤肺癌细胞系及新鲜肿瘤细胞。两者相比，结核组杀伤活性高于肺癌组，差异有显著性。ＥＡＬ的活性可反映胸水局部免疫状态。
Lymphocyte phenotypes in 17 pleural effusions of lung cancer and 17 pleural pleural effusions were detected with monoclonal antibodies (OKT3, OKT4, OKT8, OKT11). Results: The absolute number of lymphocytes in tuberculosis group was higher than that in cancerous pleural effusion. The percentage and absolute number of T3 +, T4 + and T11 + in the structural group were significantly higher than those in cancerous pleural effusion. The absolute number of T8 + in tuberculosis group was higher than that in lung cancer group, and the percentage was lower than that in lung cancer group. Lung cancer and tuberculous pleural effusion in lymphocytes can be activated by IL-2 EAL, can kill lung cancer cell lines and fresh tumor cells. Compared with the two groups, the killing activity of tuberculosis group was higher than that of lung cancer group, the difference was significant. The activity of EAL can reflect the local immune status of pleural effusion.