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目的探讨彩色多普勒超声对原发性胆汁性肝硬化(PBC)的诊断价值。方法回顾性分析经临床及肝穿病理确诊的22例PBC患者超声声像图特点,包括观察肝脏形态、内部实质回声、胆管走行等,测量肝内外胆管和门静脉主干内径。结果 22例PBC患者的超声特点为:肝脏实质回声较强,分布不均匀,肝内胆管可有轻度扩张,与肝外胆管扩张程度不成比例。胆管壁轻度增厚、回声增强,呈弥漫分布短线样改变,胆管后方回声轻度增强。晚期患者可出现门脉高压超声表现。结论 PBC患者具有特征性超声图像表现,彩色多普勒超声在诊断和病因分析中具有较高的应用价值。
Objective To investigate the value of color Doppler ultrasound in the diagnosis of primary biliary cirrhosis (PBC). Methods The echocardiographic features of 22 PBC patients diagnosed clinically and through liver biopsy were retrospectively analyzed, including the observation of the morphology of the liver, the internal echo and the running of the bile duct. The internal diameters of the bile duct and portal vein were measured. Results The sonographic features of 22 patients with PBC were as follows: the echogenicity and uneven distribution of the liver, mild expansion of the intrahepatic bile duct and out of proportion with the extrahepatic bile duct dilatation. Bile duct wall mild thickening, enhanced echogenic, diffuse distribution of short-line changes, bile duct slightly enhanced echo. Patients with advanced portal hypertension may appear. Conclusions PBC patients have characteristic ultrasonographic manifestations. Color Doppler ultrasound has high value in diagnosis and etiology analysis.