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作者报告一例下咽部鳞状细胞癌病人出现多发的皮肤结节。活组织检查证实是低分化鳞癌的皮肤转移。角蛋白染色证明皮肤肿瘤细胞中存在角蛋白。病人51岁,男性,主诉颈部肿胀、咽喉痛、食欲不振3个月,体重下降30磅。间接喉镜检查发现会厌有一个潜在性梗阻性肿瘤。病人曾先后接受过四个疗程的氨甲喋呤和博莱霉素化疗,5060rad的喉部放射治疗,以及颈部左侧廓清术和喉切除术。手术
The authors report one case of multiple skin nodules in patients with hypopharynx squamous cell carcinoma. Biopsy confirmed the skin metastasis of poorly differentiated squamous cell carcinoma. Keratin staining demonstrated the presence of keratin in skin tumor cells. The patient, 51 years old, was male and complained of neck swelling, sore throat, loss of appetite for 3 months, and weight loss of 30 pounds. Indirect laryngoscopy revealed a potentially obstructive tumor in the epiglottis. The patient had received four courses of methotrexate and bleomycin chemotherapy, 5,060 rad of laryngeal radiation therapy, and left cervical neck dissection and laryngectomy. surgery