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[目的]观察辨证分型联合西药治疗甲亢疗效。[方法]使用随机平行对照方法,将75例住院患者按抛硬币法简单随机分为两组。对照组37例甲巯咪唑,10mg/次,3次/d,甲状腺毒症控制后改为2.5~5mg/d;普萘洛尔,10mg/次,3次/d;维生素B6,20mg/次,3次/d。治疗组38例辨证分型。气滞血瘀(黄药子15g,海藻12g,白芍9g,枳壳、陈皮、柴胡、青皮、川芎各6g,甘草3g);肝火旺盛(谷精草、夏枯草各30g,黄芩、生地各15g,龙胆草、泽泻各9g,陈皮、青皮各3g);肝肾阴虚(夏枯草、旱莲草、生地、玄参、麦冬、女贞子各15g,白芍9g,牡丹皮6g,甘草3g);肝热痰湿(紫花、地丁各15g,夏枯草、黄药子各12g,白芍、钩藤各9g,半夏、牡丹皮、龙胆草各6g,甘草、陈皮各3g),1剂/d,水煎400m L,早晚餐后口服,200m L/次;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、FT3、FT4、不良反应。治疗1疗程,判定疗效。[结果]治疗组基本控制21例,有效14例,无效3例,总有效率96.32%。对照组基本控制17例,有效10例,无效10例,总有效率72.97%。治疗组疗效优于对照组(P<0.05)。FT3、FT4两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]辨证分型联合西药治疗甲亢疗效满意,无严重不良反应,值得推广。
[Objective] To observe the syndrome differentiation and western medicine in treating hyperthyroidism. [Methods] Using randomized parallel control method, 75 inpatients were randomly divided into two groups according to the coin tossing method. Control group 37 cases of methimazole, 10mg / times, 3 times / d, thyrotoxicosis control to 2.5 ~ 5mg / d; propranolol, 10mg / times, 3 times / d; vitamin B6, 20mg / times , 3 times / d. Treatment group of 38 cases of syndrome differentiation type. Qi stagnation and blood stasis (Radix Astragali 15g, seaweed 12g, white peony root 9g, Citrus aurantium, dried tangerine peel, Bupleurum, Qingpi, Chuanxiong each 6g, licorice 3g) , Gentian, Alisma 9g, dried tangerine peel, green peel 3g); liver and kidney deficiency (Prunella, Eclipta prostrata, habitat, Scrophularia, Ophiopogon, Fructus 15g, white peony root 9g, tree peony 6g , Licorice 3g); liver phlegm (purple, to the 15g each, Prunella, Radix 12g each, white peony root, Uncaria 9g, Pinellia, moutan, gentian 6g each, licorice, dried tangerine peel 3g) , 1 dose / d, decoction 400m L, oral administration after breakfast and dinner, 200m L / times; western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. Observed clinical symptoms, FT3, FT4, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group basically controlled 21 cases, 14 cases were effective, 3 cases were ineffective, the total effective rate was 96.32%. Control group, 17 cases of basic control, effective in 10 cases, ineffective in 10 cases, the total effective rate was 72.97%. The treatment group was better than the control group (P <0.05). FT3 and FT4 improved in both groups (P <0.01), the treatment group improved better than the control group (P <0.01). [Conclusion] Syndrome differentiation combined with western medicine is effective in treating hyperthyroidism without serious adverse reactions, which deserves promotion.