论文部分内容阅读
目的:评价不同剂量的奥曲肽用于治疗不完全性肠梗阻患者症状缓解的临床疗效。方法:选取2014年4月—2015年4月收治的不完全性肠梗阻患者120例;将其随机分为A组、B组和C组,每组40例;所有患者均给予临床常规治疗(纠正水电解质紊乱,胃肠减压以及营养支持等);A组患者再给予15μg奥曲肽治疗,B组患者给予25μg奥曲肽治疗,C组患者给予35μg奥曲肽治疗,评价3组患者治疗后的总有效率。结果:C组患者治疗的总有效率为95.00%高于A组和B组患者分别为85.00%和87.50%(P<0.05);临床症状(腹痛、腹胀、呕吐)缓解时间、肛门排便排气时间以及住院时间均优于A组和B组(P<0.05);胃肠减压引流量低于A组和B组(P<0.05)。结论:采用35μg奥曲肽治疗不完全性肠梗阻患者疗效优于15μg和25μg的疗效,可有效缓解患者临床症状,缩短住院时间,减少胃肠减压引流量。
Objective: To evaluate the clinical efficacy of different doses of octreotide in the treatment of patients with incomplete intestinal obstruction. Methods: One hundred and twenty patients with incomplete intestinal obstruction who were admitted from April 2014 to April 2015 were selected and randomly divided into A group, B group and C group, 40 cases in each group. All patients were given routine clinical treatment Correction of water and electrolyte disorders, gastrointestinal decompression and nutritional support, etc.); A group of patients given 15μg octreotide treatment, B patients given 25μg octreotide treatment, C patients given 35μg octreotide treatment to evaluate the three groups of patients after treatment, the total effective rate . Results: The total effective rate was 95.00% in group C, 85.00% in group A and 87.50% in group B (P <0.05). The clinical symptoms (abdominal pain, abdominal distension and vomiting), anal defecation Time and hospital stay were better than those in group A and group B (P <0.05). Gastrointestinal decompression and drainage were lower than those in group A and group B (P <0.05). Conclusion: The effect of 35μg octreotide in treating patients with incomplete intestinal obstruction is superior to that of 15μg and 25μg, which can effectively relieve the clinical symptoms, shorten the length of hospital stay and reduce the amount of gastrointestinal decompression and drainage.