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目的通过分析腺苷脱氨酶(ADA)与肝功能相关性,了解血清腺苷脱氨酶在肝炎诊断中的意义。方法对肝炎患者血清标本进行ADA活性测定,并同时对肝功能指标(ALT、AST、T-BIL、D-BIL、GGT等)进行检测分析。结果对300例肝炎患者阳性检出率分析:ADA为62.1%,ALT为40.3%,AST为30.4%,T-BIL为28.0%,D-BIL为27.1%,GGT为33.1%;ALT活性不高或正常时,ADA对肝炎患者的检出率为58.9%,明显高于AST、T-BIL、D-BIL、GGT的阳性检出率(15.2%、26.1%、20.0%、16.4%)。结论ADA活性测定,可大大提高肝炎患者阳性检出率。
Objective To understand the significance of serum adenosine deaminase in the diagnosis of hepatitis by analyzing the relationship between adenosine deaminase (ADA) and liver function. Methods Serum samples of patients with hepatitis were assayed for ADA activity, and liver function parameters (ALT, AST, T-BIL, D-BIL, GGT, etc.) were detected and analyzed. Results The positive rate of ADA was 62.1%, ALT was 40.3%, AST was 30.4%, T-BIL was 28.0%, D-BIL was 27.1%, GGT was 33.1%, ALT activity was not high Or normal, the positive rate of ADA in hepatitis patients was 58.9%, which was significantly higher than that of AST, T-BIL, D-BIL and GGT (15.2%, 26.1%, 20.0%, 16.4%). Conclusions ADA activity assay can greatly improve the positive rate of hepatitis patients.