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目的研究蜕皮甾酮对小鼠脑缺氧的影响。方法利用亚硝酸钠和氰化钾造成急性脑缺氧模型，考察蜕皮甾酮的抗脑缺氧作用，并观察蜕皮甾酮对氰化钾引起的脑组织过氧化脂质生成的影响和亚硝酸钠致小鼠脑缺氧引起的记忆巩固障碍的影响。结果蜕皮甾酮ｉｇ１４４ｍｇ·ｋｇ－１能明显对抗小鼠急性脑缺氧，在体内和体外实验中均能抑制小鼠脑缺氧引起的脑组织过氧化脂质的生成，改善脑缺氧引起的记忆巩固障碍。结论蜕皮甾酮对小鼠脑缺氧有保护作用。
Objective To study the effect of ecdysterone on cerebral hypoxia in mice. Methods Acute cerebral hypoxia model was induced by sodium nitrite and potassium cyanide, and the effect of ecdysterone on cerebral anoxia was observed. The effect of ecdysterone on peroxidation of lipid peroxidation induced by potassium cyanide and nitrite Effects of Natriurence-induced Memory Consolidation Disorder on Cerebral Hypoxia in Mice. Results ecdysterone ig 14 4mg · kg-1 can significantly antagonize acute cerebral ischemia in mice, both in vivo and in vitro experiments can inhibit cerebral anoxia-induced brain tissue lipid peroxidation, improve cerebral anoxia Caused by memory consolidation obstacles. Conclusion Ecdysterone protects mice brain from hypoxia.