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目的 观察卡维地洛与非洛地平治疗在运动诱发和动态心电图监测时对心肌缺血的影响。方法 对 110例活动平板运动试验与动态心电图监测有心肌缺血的病人分为两组 ,分别服用卡维地洛和非洛地平 4周 ,观察治疗后效果。结果 两组均可提高抗心肌缺血效应和增加病人运动耐量 ,但卡维地洛提高病人运动耐量时间明显优于非洛地平 (P <0 0 5 )。结论 卡维地洛可提高抗心肌缺血效应 ,安全性好。
Objective To observe the effects of carvedilol and felodipine on myocardial ischemia induced by exercise-induced and ambulatory electrocardiogram (ECG). Methods 110 patients with treadmill exercise test and Holter monitoring myocardial ischemia were divided into two groups, taking carvedilol and felodipine for 4 weeks, the effect after treatment was observed. Results Both groups improved anti-ischemic effect and increased patient’s exercise tolerance. However, carvedilol improved patients’ exercise tolerance significantly longer than felodipine (P <0.05). Conclusion Carvedilol can improve anti-ischemic effect and safety.