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应用基因工程制成能分泌白介素（IL）－12的成纤维细胞肿瘤疫苗，观察这一辅助免疫疗法对胃肠道癌的作用。认BALB八鼠提出C－26结肠腺癌细胞系和从NIH瑞士鼠提出NIH3T3成纤维细胞系备用。用逆转录病毒媒介物MFG等以制成重组逆转录病毒；使后者含有鼠白介素（IL）－12p40亚单位C
A fibroblast tumor vaccine that can secrete interleukin (IL)-12 has been genetically engineered to observe the effect of this adjuvant immunotherapy on gastrointestinal cancer. The BALB eight mice were presented with the C-26 colon adenocarcinoma cell line and the NIH3T3 fibroblast cell line raised from NIH Swiss mice was used. Recombinant retroviruses are made using the retroviral vector MFG; the latter contains murine interleukin (IL)-12p40 subunit C