论文部分内容阅读
早期的文献表明利福平和苯巴比妥均为很强的肝药酶诱导剂.我们最近的研究亦发现利福喷丁与利福定对小鼠也有类似的诱导作用.本文通过进一步的研究,发现小鼠给予这三种利福霉素和苯巴比妥预处理后,在以下几个方面表现出肝微粒体酶的改变.
Early literature shows that both rifampicin and phenobarbital are strong hepatic drug inducer.Our recent study also found that rifapentine and rifamycin have similar induction in mice.Through further research , Found that mice given these three rifamycin and phenobarbital pretreatment, in the following areas showed changes in liver microsomal enzymes.