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环磷酰胺是抗肿瘤药物,因其毒副作用较多,所以临床上一般不把该药作为治疗肾病的常用药,如确属需要,应注意掌握适应证,主要适应证包括:①经激素系统治疗无效的病例;②对激素治疗产生依赖性的病例;③对使用激素有禁忌证的病例。鉴于其毒副作用的存在,在应用其治疗肾病过程中,应注意以下几个问题: 1.对骨髓的抑制。白细胞下降远较血小板下降多见。肾病患者在用药以前或同时多配合应用过激素,
Cyclophosphamide is an antineoplastic drug, because of its toxic side effects, it is generally not clinically used as a medicine commonly used in the treatment of nephropathy, if it is needed, should pay attention to indications, the main indications include: ① by the hormone system Treatment ineffective cases; ② hormone therapy dependent cases; ③ contraindications to the use of hormones in the case. In view of its toxic side effects, in the application of its treatment of renal disease, should pay attention to the following questions: 1. The inhibition of bone marrow. Leukopenia is more common than thrombocytopenia. Nephropathy in patients with medication before or at the same time with the application of hormone,