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目的:探讨不同液体复苏对脓毒性休克患者预后的影响。方法:选取我院100例脓毒性休克患者为研究对象,随机分为三组,A组33例,使用0.9%生理盐水复苏;B组33例,使用羟乙基淀粉130/0.4氯化钠注射液复苏;C组34例,应用聚明胶肽复苏,比较3组患者的预后情况。结果:三组患者复苏后HR、MAP、血乳酸值、APACHEⅡ评分比较差异无统计学(p>0.05);B组、C组24h血乳酸清除率明显高于A组(p<0.05)。结论:3种液体应用于脓毒性休克复苏治疗中疗效相当,但从预后情况综合考虑,羟乙基淀粉130/0.4氯化钠注射液、聚明胶肽能有效改善血流动力学状态,更适用于脓毒性休克患者。
Objective: To investigate the effect of different fluid resuscitation on the prognosis of patients with septic shock. Methods: A total of 100 patients with septic shock in our hospital were enrolled and divided into three groups randomly. Group A (n = 33) received 0.9% saline and group B (n = 33) received hydroxyethyl starch 130 / 0.4 sodium chloride injection Fluid resuscitation; C group 34 cases, the application of polygeline resuscitation, the prognosis of the three groups were compared. Results: There was no significant difference in HR, MAP, blood lactate and APACHEⅡ scores after resuscitation among the three groups (p> 0.05). The serum lactate clearance rate of group B and group C was significantly higher than that of group A (p <0.05). Conclusion: Three kinds of liquid are effective in treating septic shock and resuscitation. However, considering the prognosis, hydroxyethyl starch 130 / 0.4 sodium chloride injection and poly-gelatin can effectively improve the hemodynamic status, which is more suitable In patients with septic shock.