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目的观察米索前列醇预防产后出血的效果。方法选择本院正常足月妊娠,无内外科合并症及产科并发症,且无米索前列醇禁忌的阴道分娩的产妇250例,随机分为2组,实验组(用米索前列醇)130例。对照组(用缩宫素)120例。实验组在胎儿娩出后立即给予米索前列醇0.6 mg塞肛,对照组在胎儿娩出后给予缩宫素20 U静脉推注,观察2组患者的第三产程,产后2 h及产后24 h出血量。结果实验组与对照组比较,对预防产后出血差异有统计学意义(P<0.01),运用米索前列醇前后,产妇血压无明显变化(P>0.05)。结论米索前列醇对预防产后出血有明显效果,方法简便、安全。
Objective To observe the effect of misoprostol in preventing postpartum hemorrhage. Methods 250 pregnant women with normal term pregnancy, no intra-and-surgical complications and obstetric complications without vaginal delivery of misoprostol were randomly divided into two groups. The experimental group (misoprostol) 130 example. Control group (with oxytocin) 120 cases. In the experimental group, misoprostol 0.6 mg was administered immediately after the fetus was delivered. In the control group, oxytocin 20 U intravenous injection was given after the fetus was delivered. The third stage of labor, 2 h postpartum and 24 h postpartum hemorrhage were observed the amount. Results Compared with the control group, there was significant difference between the experimental group and the control group in preventing postpartum hemorrhage (P <0.01). There was no significant change in the blood pressure before and after the administration of misoprostol (P> 0.05). Conclusion Misoprostol has a significant effect in preventing postpartum hemorrhage. The method is simple and safe.