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目的:探讨冠心病合并2型糖尿病患者的临床及冠状动脉病变特点。方法:2007年1月—2008年12月经冠状动脉造影确诊为冠心病的患者中,合并2型糖尿病者236例(DM组),无糖尿病患者236例(NDM组),比较2组患者的临床资料和冠状动脉造影资料。冠心病定义为≥1支主要冠状动脉或其主要分支狭窄≥50%,糖尿病诊断标准参照1999年WHO糖尿病诊断标准,用冠状动脉病变总记分评价冠状动脉病变程度。结果:DM组冠状动脉病变总记分明显高于NDM组(P<0.05),3支病变及弥漫性病变比例显著高于NDM组(P<0.05)。结论:冠心病合并2型糖尿病患者冠状动脉病变广泛且较严重,应早期多环节防治。
Objective: To investigate the clinical characteristics and coronary artery lesion in patients with coronary heart disease complicated with type 2 diabetes mellitus. Methods: From January 2007 to December 2008, 236 patients with type 2 diabetes mellitus (DM group) and 236 non-diabetic patients (NDM group) were enrolled in the study. The clinical data of two groups were compared Data and coronary angiography data. Coronary heart disease was defined as ≥1 coronary artery or its major stenosis ≥50%. The diagnostic criteria of diabetes were evaluated according to the WHO diagnostic criteria of WHO in 1999. The severity of coronary artery lesion was evaluated by total coronary artery disease score. Results: The total score of coronary artery disease in DM group was significantly higher than that in NDM group (P <0.05). The proportion of 3 lesions and diffuse lesions in DM group was significantly higher than that in NDM group (P <0.05). Conclusion: Coronary heart disease complicated with type 2 diabetes patients with extensive and more serious coronary lesions should be early prevention and treatment of multiple links.