使用改良的Ｓｉｎｇｈ指数分级法对镉暴露工人Ｘ片上的股骨上端骨纹进行了分析，结果表明：镉暴露工人的Ｓｉｎｇｈ指数明显低于对照工人，且Ｓｉｎｇｈ指数与尿镉、尿ＮＡＧ、尿钙、尿β一微球蛋白有明显相关性，用Ｓｉｎｇｈ指数来判断骨质损害时，尿镉水平和骨质损害率之间存在着剂量反应关系。因此建议将Ｓｉｎｇｈ指数做为环境镉致骨损伤的一项早期诊断指标。 The improved Singh index grading method was used to analyze the upper femur bone pattern of cadmium exposed workers. The results showed that the Singh index of cadmium exposed workers was significantly lower than that of the control workers, and Singh index was positively correlated with urinary cadmium, urine NAG, urinary calcium, Urinary β-microglobulin is significantly related to Singh index to determine the bone damage, there is a dose-response relationship between urinary cadmium levels and the rate of bone damage. Therefore, it is suggested that the Singh index be used as an early diagnostic indicator of cadmium-induced bone damage in the environment.