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目的比较采用自体血回输与库血输入对脑动脉瘤患者手术对机体产生的抗感染免疫效应。方法选取40名脑动脉瘤手术患者随机分为2组:观察组(自体血组)和对照组(库血组)。记录每例患者术中出血量、回收血量、输入异体红细胞用量、异体血浆用量等。检测术前1 h、术后d1、3、7红细胞计数(RBC)、血红蛋白(Hb)、血小板计数(Plt)、凝血酶原时间(PT)、部分凝血活酶时间(APTT)以及降钙素原(PCT)。观察2组术后感染发生率。结果RBC、Hb术后d1、3观察组均高于对照组(P<0.05);与术前比,PCT术后d1、3观察组1例显著升高(2.95μg/L)明显低于对照组5例(3.39±2.12)μg/L(P<0.05);术后感染率观察组明显低于对照组(P<0.05)。结论脑动脉瘤手术患者应用自体血回输有利于患者恢复,降低了术后感染的风险。
Objective To compare the anti-infective effect of autologous blood transfusion and reservoir blood on the organism in patients with cerebral aneurysm. Methods Forty cerebral aneurysms were randomly divided into two groups: observation group (autologous blood group) and control group (blood pool group). Record each patient intraoperative blood loss, recovery of blood volume, the amount of allogenic input of red blood cells, allogeneic plasma dosage. The levels of RBC, Hb, Plt, PT, APTT, and calcitonin The original (PCT). The incidence of postoperative infection was observed in two groups. Results The levels of d1,3 in RBC and Hb after operation were significantly higher than those in control group (P <0.05). Compared with those before operation, one case of d1,3 in the observation group after PCI was significantly higher (2.95μg / L) than the control (3.39 ± 2.12) μg / L (P <0.05). The postoperative infection rate in the observation group was significantly lower than that in the control group (P <0.05). Conclusion The application of autologous blood transfusion in patients with cerebral aneurysm surgery is conducive to the recovery of patients, reducing the risk of postoperative infection.