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目的 观察三黄凝胶联合红蓝光照射治疗痤疮的临床疗效.方法 将2016年1月-2017年3月甘肃中医药大学附属医院收治的102例Ⅱ、Ⅲ级痤疮患者按1∶1∶1配对,采用随机数字生成器分三黄凝胶组、红蓝光组、联合组3组,治疗4周后以炎症皮损治疗前后减少率评价疗效.结果 三黄凝胶组、红蓝光组和联合组有效率分别为72.73%、64.52%和94.12%,疗效差异有统计学意义(P <0.001);3组治疗前后临床症状评分差异有统计学意义(P≤0.001).结论 三黄凝胶联合红蓝光治疗痤疮疗效卓著,优于单一疗法,且不良反应少,复发率低.“,”Objective To observe the clinical effect of Sanhuang gel combined with red and blue light in the treatment of acne.Methods One hundred and two cases of grade Ⅱ and Ⅲ acne patients in Affiliated Hospital of Gansu University of TCM from January 2016 to March 2017 according to the random number generator using 1∶ 1∶1 pairing,divided Sanhuang gel group,red and blue light group and combined group.The reduced rate of curative effect of pre-and post-therapy for inflammatory lesions was evaluated after 4 weeks of treatment.Results There were significant differences in the curative effect of Chinese medicine group,red blue light group and combined group (P < 0.001),the effective rate of treatment were 72.73%,64.52% and 94.12%;the difference of clinical symptom scores before and after treatment in the three groups was obvious (P ≤0.001).Conclusion The curative effect of Sanhuang gel combined with red and blue light is better than single therapy,and has less adverse reaction and low recurrence rate.