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答:对于常规呼吸支持手段(肺表面活性物质、高频机械通气和一氧化氮吸入)无效新生儿,ECMO是唯一有效的救治手段。临床上可能需要ECMO呼吸支持的常见新生儿疾病如下:1.先天性膈疝(CDH):CDH患儿应用ECMO支持的生存率与肺发育及肺动脉高压的严重程度密切相关,NO吸入能够减轻肺动脉高压症状,但不能减少ECMO应用。根据国际体外生命支持组织(ELSO)的数据显示,接受ECMO支持的CDH患儿存活率为51%。
A: ECMO is the only effective treatment for neonates who are ineffective with conventional respiratory support (pulmonary surfactant, high-frequency mechanical ventilation, and nitric oxide inhalation). Common neonatal diseases that may require ECMO respiratory support are as follows: 1. Congenital diaphragmatic hernia (CDH): The survival rate of children with CDH with ECMO is closely related to the severity of pulmonary development and pulmonary hypertension. NO inhalation attenuates pulmonary hypertension Symptoms, but can not reduce ECMO application. According to the International Organization for Survival in Life (ELSO) data, 51% of children with CDH received ECMO support.