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近年来,随着乙型肝炎病毒(HBV)分子生物学研究的进展,尤其是HBV前C基因突变株的发现,对慢性HBV感染中e系统的临床意义有了进一步的认识。目前趋向于将慢性乙型肝炎分为两大型[1]:乙型肝炎e抗原(HBeAg)阳性慢性肝炎和乙型肝炎e抗体(抗-HBe)阳性慢性肝炎(异型慢性乙型
In recent years, with the progress of molecular biology of Hepatitis B virus (HBV), especially the discovery of pre-HBV C mutations, we have further understanding of the clinical significance of e-system in chronic HBV infection. At present, chronic hepatitis B tends to be divided into two major types: hepatitis B e antigen (HBeAg) -positive chronic hepatitis and hepatitis B e antibody (anti-HBe) -positive chronic hepatitis