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局部晚期结直肠癌需用扩大切除术(即切除包括邻近的器官组织)来清除所有的癌组织,使肿瘤不扩散。然而,并发症的发生率却很高。为了评价此手术的可行性,本文探讨了局部晚期结直肠癌患者行扩大切除术后的发病率、死亡率、长期生存率及预后因素等。材料与方法:220例中T_3期(癌组织侵犯结肠及邻近组织)肿瘤占150例,T_4期(癌组织侵犯至邻近器官和组织)70例。83例行扩大切除术,其中>70岁33例,38例由于炎性粘连已浸润蔓延行扩大全切除术。肿瘤位于升结肠45例,横结肠7例,降结肠15例,乙状结肠52例,直肠100例。部分患者行D_0切除术
Locally advanced colorectal cancer requires extensive resection (ie, removal of adjacent organ tissue) to remove all cancerous tissue and prevent the tumor from spreading. However, the incidence of complications is very high. To evaluate the feasibility of this procedure, this article explores the incidence, mortality, long-term survival, and prognostic factors of patients with locally advanced colorectal cancer after extended resection. Materials and Methods: In 220 patients, T_3 stage (invasion of cancer tissue and adjacent tissue) accounted for 150 cases, and T_4 stage (invasion of cancer tissue to adjacent organs and tissues) in 70 cases. Eighty-three patients underwent extended resection, including 33 cases >70 years old. 38 cases had enlarged resection because of inflammatory adhesions that had infiltrated and spread. The tumor was located in 45 cases of ascending colon, 7 cases of transverse colon, 15 cases of descending colon, 52 cases of sigmoid colon, and 100 cases of rectum. D_0 resection in some patients