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[目的]探讨血清中脂质及载脂蛋白测定在冠心病、高血压、高脂血症诊断中的作用。[方法]用生化分析仪检测297例上述患者及健康人血清中总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、载脂蛋白,并进行分组比较分析。[结果]各疾病组的血脂浓度、ApoAI明显高于对照组(P﹤0.01),ApoB明显低于于对照组(P﹤0.01)。[结论]载脂蛋白定量分析比血脂项目更易早发现异常情况,是预测心脑血管疾病的较好指标,两者结合进行分析,诊断结果更可靠。
[Objective] To investigate the role of serum lipid and apolipoprotein in the diagnosis of coronary heart disease, hypertension and hyperlipidemia. [Method] The total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, apolipoprotein in 297 cases of above patients and healthy persons were detected by biochemical analyzer and compared by grouping. [Results] ApoAI was significantly higher in all disease groups than in control group (P <0.01), ApoB was significantly lower than that in control group (P <0.01). [Conclusion] The quantitative analysis of apolipoprotein is easier to detect the anomalous conditions earlier than the lipids. It is a good predictor of cardiovascular and cerebrovascular diseases. The combination of the two can be used to analyze the results and the diagnosis is more reliable.