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目的探讨ST段抬高型急性心肌梗死(心梗)患者猝死预警指标Tp-e/QT比值的临床价值。方法诊断为ST段抬高型急性心肌梗死的患者50例为研究组;对照组为同期50例来院进行健康体检的受试者。对比两组QTd、Tp-e及Tp-e/QT比值。结果研究组和对照组QTd、Tp-e及Tp-e/QT对比差异有统计学意义(P<0.05)。研究组中恶性心律失常者与非恶性心律失常者QTd、Tp-e分别为(58.5±3.9)、(158.7±32.6)ms和(58.8±4.2)、(162.3±33.4)ms,对比差异无统计学意义(P>0.05);研究组中恶性心律失常者与非恶性心律失常者Tp-e/QT分别为(0.32±0.06)、(0.29±0.05),差异有统计学意义(P<0.05)。结论本次研究认为ST段抬高型急性心肌梗死患者Tp-e/QT比值明显增大,其是心脏猝死的较好预警指标。
Objective To investigate the clinical value of Tp-e / QT ratio in patients with ST-elevation acute myocardial infarction (MI). Methods Fifty patients with ST-segment elevation acute myocardial infarction were selected as the study group. The control group consisted of 50 healthy subjects who were hospitalized during the same period. The QTd, Tp-e and Tp-e / QT ratios were compared between the two groups. Results There were significant differences in QTd, Tp-e and Tp-e / QT between study group and control group (P <0.05). The QTd and Tp-e of the study group were (58.5 ± 3.9), (158.7 ± 32.6) ms and (58.8 ± 4.2) and (162.3 ± 33.4) ms, respectively, with no difference in the comparison between malignant arrhythmia and non-malignant arrhythmia (P <0.05). The Tp-e / QT in the study group was significantly higher than that in the non-malignant arrhythmia group (0.32 ± 0.06 vs 0.29 ± 0.05, P 0. 05) . Conclusions This study suggests that the Tp-e / QT ratio of patients with ST-elevation acute myocardial infarction is significantly increased, which is a good predictor of sudden cardiac death.