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1910年,Herrick在一例贫血的非洲大学生血液中发现镰状细胞,因此命名为镰状细胞性贫血(sickle cell disease,SCD)。临床研究发现,将SCD患者的血液取出放置在室温条件下封存于玻璃板下数天后其红细胞出现镰状化。1927年,Hahn证实正常的红细胞在氧张力下降时可转变为镰状细胞。1949年
In 1910, Herrick discovered sickle cells in the blood of an anemic African college student and named it sickle cell disease (SCD). Clinical studies have found that patients with SCD blood removed from the room temperature stored in the glass plate for a few days after the sickle of erythrocytes. In 1927, Hahn confirmed that normal erythrocytes convert to sickle cells when their oxygen tension drops. 1949