近年来,随着精密、复杂医疗器械逐步增多,各种导管、起搏器、人工瓣膜、植入物、透析技术及内镜等医用生物材料也得到广泛应用,因细菌黏附于生物材料表面形成生物膜而导致以生物材料为中心的感染)日益严重~([1])。生物膜的存在使得细菌可抵抗清洗与消毒的作用,造成生物材料清洗和消毒的失败,成为医院感染的潜在因素~([2])。消毒供应中心 In recent years, with the increase of precision and complicated medical devices, a variety of medical biomaterials such as catheters, pacemakers, prosthetic valves, implants, dialysis techniques and endoscopes have also been widely used because bacteria adhere to the surface of biomaterials to form Biofilms lead to biomaterial-centric infections) are worsening ~ ([1]). The presence of biofilms makes bacteria resistant to cleaning and disinfection, resulting in the failure of cleaning and disinfection of biological materials as a potential factor in nosocomial infections (2). Disinfection Supply Center