论文部分内容阅读
目的观察小剂量硝普钠与卡托普利联合应用对慢性肺心病患者急性加重期的疗效。方法将98例确诊为肺心病的患者随机分成2组,常规组50例给予抗感染,吸氧、小剂量利尿剂及西地兰等常规治疗;治疗组48例除常规治疗外另外给予硝普钠0.4~0.8ug/(Kg.min)静脉微泵注入,及卡托普利12.5mg,2~3次/d口服。结果常规组总有效率为58%,治疗组总有效率为89.6%,低剂量硝普钠与卡托普利联合应用对慢性肺心病急性发作期的疗效优于常规组(P<0.01),并且治疗组未发现明显的付作用。结论低剂量的硝普钠与卡托普利联合治疗慢性肺心病急性加重期是安全有效的方法。
Objective To observe the curative effect of low dose sodium nitroprusside and captopril in acute exacerbation of patients with chronic cor pulmonale. Methods A total of 98 patients diagnosed as pulmonary heart disease were randomly divided into two groups. The conventional group was given anti-infection, oxygen inhalation, low-dose diuretic and cedilanid and other conventional treatments. In the treatment group of 48 patients, Sodium 0.4 ~ 0.8ug / (Kg.min) intravenous micro-pump infusion, and captopril 12.5mg, 2 ~ 3 times / d orally. Results The total effective rate was 58% in the conventional group and 89.6% in the treatment group. The combination of low dose sodium nitroprusside and captopril was superior to the conventional group in the acute exacerbation of chronic pulmonary heart disease (P <0.01) And the treatment group did not find significant pay role. Conclusion Low-dose sodium nitroprusside combined with captopril in the treatment of acute exacerbation of chronic pulmonary heart disease is a safe and effective method.