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目的探讨采用显微喉镜下CO_2激光手术治疗复发性小儿喉乳头状瘤的临床疗效。方法回顾性分析我院2010-2015年收治的复发性小儿喉乳头状瘤患儿45例,所有喉乳头状瘤复发患儿,均经术后病理证实。根据治疗方案的不同分为两组,其中23例患儿予以显微喉镜下CO_2激光手术治疗作为观察组,另22例患儿予以传统手术治疗作为对照组;观察两组患儿治疗后的临床效果及并发症情况。结果随访期间,观察组患儿的显效率为69.57%,明显高于对照组(36.36%),差异具有统计学意义(P<0.05);观察组的有效率和无效率分别为17.40%和13.04%,对照组的有效率和无效率均为31.82%,两组比较差异均无统计学意义(P>0.05);观察组复发率(30.43%)低于对照组(63.64%),P<0.05。两组均未出现死亡病例。观察组3例患儿术后出现声带粘连、1例患儿出现声带损伤瘢痕愈合;对照组2例患儿术后出现声带粘连、2例患儿术后出现呼吸困难,观察组术后并发症总发生率为17.39%,略低于对照组的18.18%,差异无统计学意义(P>0.05)。结论显微喉镜下CO_2激光术治疗小儿喉乳头状瘤较传统手术在并发症不提高的情况下显效率提高,值得推广。
Objective To investigate the clinical effect of laryngeal papilloma of recurrent laryngeal papilloma treated by CO_2 laser under the microlaryngoscope. Methods Retrospective analysis of 45 children with recurrent laryngeal papilloma in our hospital from 2010 to 2015, all children with recurrent laryngeal papilloma were confirmed by pathology. According to the different treatment options, the patients were divided into two groups, of which 23 cases were treated with CO 2 laser under the microlaryngoscope as the observation group, and the other 22 cases were treated with conventional surgery as the control group. After treatment, Clinical effects and complications. Results During the follow-up period, the effective rate in observation group was 69.57%, which was significantly higher than that in control group (36.36%), the difference was statistically significant (P <0.05). The effective rate and inefficiency rate in observation group were 17.40% and 13.04 %, The effective rate and inefficiency of the control group were 31.82%, the difference between the two groups was not statistically significant (P> 0.05); the recurrence rate of the observation group (30.43%) was lower than that of the control group (63.64% . No deaths occurred in either group. In the observation group, 3 cases had vocal cord adhesion after operation, and 1 case had vocal cord injury and scar healing. In the control group, 2 cases had postoperative vocal cord adhesion, 2 cases had postoperative dyspnea, postoperative complications The overall incidence was 17.39%, slightly lower than that of the control group (18.18%), with no significant difference (P> 0.05). Conclusion The treatment of laryngeal papilloma in children with laryngeal papilloma under microthroat laryngoscope is more effective than conventional surgery in the case of complications is not increased, which is worth promoting.