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本文研究了几种降压药对血脂和载脂蛋白(Apo)的影响。文中血脂和 Apo 升高或降低的 P 值除注明者外均为 P<0.05。12例病人服速尿每日40～80mg,3个月后甘油三酯平均增加29mg/dl,高密度脂蛋白胆固醇(HDL-C)轻微降低。10例病人服氯噻酮每日100mg,1个月后ApoB 和总胆固醇升高,这表明该药仅影响低密度脂蛋白。15例病人服三氯甲噻嗪每日4mg,3个月后甘油三酯和 ApoC-Ⅲ升高,HDL-C 降低。因为在极低密度脂蛋白(VLDL)中 ApoC-Ⅲ最多,故提示
This article studies the effects of several antihypertensive drugs on blood lipids and apolipoproteins (Apo). P values ?? of blood lipid and Apo increased or decreased in addition to those indicated were P <0.05.12 patients with furosemide daily 40 ~ 80mg, 3 months after the average increase of triglycerides 29mg / dl, high-density lipids Protein cholesterol (HDL-C) decreased slightly. Ten patients took chlorthalidone 100 mg daily, and after 1 month ApoB and total cholesterol were elevated, indicating that the drug affects only low-density lipoprotein. 15 patients taking trichlormethiazide daily 4mg, 3 months after the triglyceride and ApoC-III increased, HDL-C decreased. Because of the most ApoC-III in very low density lipoprotein (VLDL), it is suggested