由于催乳素(简称PRL)各种测定方法和抑制PRL分泌的药物相继问世,导致大量有关PRL对抗剂对高PRL血症患者作用的报导。在Melbourne皇家妇女医院,著者曾用溴隐亭治疗260例不孕症。在PRL水平正常的妇女,其受孕率与服用安慰剂者基本相同。然而,在PRL升高伴排卵异常的病人,其受孕率却明显升高。提出临床应用溴隐亭治疗不孕症时,必须考虑下列七个问题。 As prolactin (referred to as PRL) a variety of determination methods and inhibition of PRL secretion of drugs have been promulgated, leading to a large number of PRL antagonists on the role of high PRL blood disease reported. At Royal Melbourne Women’s Hospital, the authors used bromocriptine to treat 260 cases of infertility. In women with normal PRL, the rate of conception was similar to that of placebo. However, in patients with elevated PRL and ovulation abnormalities, the pregnancy rate is significantly increased. Proposed clinical application of bromocriptine in the treatment of infertility, we must consider the following seven questions.