Yang等[1]2007~2008年期间的一项调查显示,中国糖尿病患者已达到9240万,占成年人口的9.7%,1亿4820万人处于前糖尿病状态。糖尿病是缺血性脑卒中的独立危险因素[2],糖尿病患者脑血管病的发病率在50%以上,血糖升高水平与病情发生、发展及预后直接相关[3]。虽然糖尿病与周围微血管并发症相关,并增加神经系统事件的风险,然而糖尿病对颅内微血管损 According to a survey conducted by Yang et al. [1] from 2007 to 2008, 92.4 million people in China had diabetes, accounting for 9.7% of the adult population and 148.2 million people were in pre-diabetes. Diabetes mellitus is an independent risk factor for ischemic stroke [2]. The incidence of cerebrovascular disease in diabetic patients is over 50%. The level of blood glucose is directly related to the occurrence, development and prognosis of ischemic stroke [3]. Although diabetes is associated with peripheral microvascular complications and increases the risk of neurological events, the effects of diabetes on intracranial microvascular damage