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用HE和Giemsa、染色的鼠胚连续切片观察BALB/c小鼠胸腺的发生。11d鼠胚第3对咽囊内胚层与第3对鳃沟外胚层相互紧贴,组成胸腺原基,并可见淋巴母细胞样细胞迁入胸腺原基。12d鼠胚鳃沟外胚层包绕咽囊内胚层。13d胚胸腺原基已形成一个实体的细胞团。原基内淋巴母细胞样细胞增多,达细胞总数的10%左右。15d胚胸腺皮、髓质已可大致辨认,皮质内淋巳母细胞样细胞明显多于髓质。17~19d胚胸腺的皮、髓质分明,近似成年鼠胸腺。第4对咽囊内胚层只发生为鳃后体,不参与胸腺的形成。
BALB / c mouse thymus was observed with serial sections of HE and Giemsa stained mouse embryos. 11d mouse embryo third pairs of pharyngeal endoderm and the third of the gill of the ectoderm close to each other, composed of thymus primordium, and visible lymphoblastoid cells moved thymus primordia. 12d mouse gill gut ectoderm surrounding pharyngeal endoderm. 13d embryonic gland primordia have formed a solid cell mass. The primordial lymphoblastoid cells increase, reaching about 10% of the total number of cells. 15d embryo glandular epithelium, medulla can be roughly identified, leucocythemia within the cortex significantly more cells than the medulla. 17 ~ 19d embryo thymus skin, medulla clear, similar to adult rat thymus. The fourth pair of pharyngeal endoderm occurred only for the gill body, does not participate in the formation of the thymus.