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目的:观察老年心衰患者的甲状腺功能状态是否与其预后相关。方法:回顾分析了2007年1月～2008年12月居住于深圳市龙岗区某社区的心衰患者的病历管理档案,并对有基线甲状腺功能检查的患者进行分析。结果:本次调查共入选142例老年心衰患者,其中合并甲状腺功能减低(甲减)者48例,临床甲减14例,亚临床甲减34例。在2010年9～10月对这些患者进行横断面随访调查,指标包括再住院、心力衰竭急性发作、冠状动脉血运重建、急性心肌梗死和死亡在内的复合终点。结果显示,甲减组(包括临床和亚临床甲减)有20例患者(20/48)出现复合终点,而甲状腺功能正常组仅有19例(19/94),两组比较有统计学差异。结论:老年心衰患者若合并甲状腺功能减退,则其预后较差。
Objective: To observe whether thyroid function in elderly patients with heart failure is related to its prognosis. Methods: The records of patients with heart failure who lived in a community in Longgang District of Shenzhen City from January 2007 to December 2008 were retrospectively analyzed. Patients with baseline thyroid function tests were also analyzed. Results: A total of 142 elderly patients with heart failure were enrolled in this study. Among them, 48 cases had hypothyroidism (hypothyroidism), 14 cases had clinical hypothyroidism, and 34 cases had subclinical hypothyroidism. A cross-sectional follow-up of these patients was performed from September to October 2010 and included multiple recombination points including rehospitalization, acute heart failure, coronary revascularization, acute myocardial infarction and death. The results showed that 20 patients (20/48) in the hypothyroidism group (including clinical and subclinical hypothyroidism) had a composite end point, while only 19 patients (19/94) had the normal thyroid function group, with significant difference between the two groups . Conclusion: Elderly patients with heart failure, if combined with hypothyroidism, the prognosis is poor.