下丘脑弓状核区是脑内ACTH神经元胞体主要的集中部位。新生期大白鼠接受谷氨酸一钠(monosodium glutamete,MSG)腹腔注射后,视网膜内层结构和下丘脑弓状核区的神经元胞体毁损,但无路过纤维损伤。这时脑内ACTH含量显著减少。而ACTH 能增加大脑的兴奋性和觉醒状态,参与调节机体的警觉性。我们以大脑皮层自发电活动作为皮层机能状态的指标,以节律性闪光刺激诱发的皮 The hypothalamic arcuate nucleus is the main focal area of ​​ACTH neurons in the brain. Neonatal rats receiving intraperitoneal injection of monosodium glutamete (MSG), the inner retinal structure and the neuronal soma of the hypothalamic arcuate nucleus damage, but without passing fiber damage. At this time brain ACTH content was significantly reduced. The ACTH can increase the excitability and wake of the brain state, involved in regulating the alertness of the body. We use the cortical self-generated activity as an indicator of cortical status, rhythmic flash stimulus-induced skin