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重庆医科大学儿童医院杨锡强、汪智鸿等应用国产冻干低PH静脉注射人血丙种球蛋白(卫生部成都生物制品研究所提供)治疗新生儿败血症120例,随机分为两组,在给予敏感抗生素治疗的同时,治疗组用静脉注射人血丙种球蛋白(IVIG)200～400mg/kg/次,对照组用新鲜血浆10ml/kg·次,间隔2～3天重复给药一次,结果表明IVIG对新生儿血渗透压,血pH值影响不大,对T、B细胞功能无明显影响,IgG亚类动态检测除IgG_3衰减较快,IgG_1、IgG_2、IgG_4可维持较高水平达10天。
Chongqing Medical University Children’s Hospital Yang Xiqiang, Wang Zhihong and other applications of domestic freeze-dried low PH intravenous injection of human blood gamma globulin (Ministry of Health, Chengdu Institute of Biological Products) treatment of 120 cases of neonatal sepsis were randomly divided into two groups, given sensitive antibiotic treatment At the same time, the treatment group intravenous injection of human blood gamma globulin (IVIG) 200 ~ 400mg / kg / times, the control group with fresh plasma 10ml / kg · times, interval 2 to 3 days repeated administration, the results show that IVIG on newborn Infant blood pressure and blood pH had little effect on T and B cell function. IgG subclass dynamic test except IgG3 attenuated rapidly, and IgG1, IgG2 and IgG4 could be maintained at a high level for 10 days.