论文部分内容阅读
研究了对甲苯磺酸(PTSA)催化的吡咯烷酮化合物与各种N-亲核试剂的胺化反应.该方法通过简单抽滤就能以中等至优良产率得到一系列的偕二胺化合物,后处理简单无需柱层析,且可以将反应放大至克级规模.
Amination of p-toluenesulfonic acid (PTSA) -catalyzed pyrrolidone compounds with various N-nucleophiles was studied by a series of gem-diamine compounds with moderate to good yields by simple suction filtration Simple processing without column chromatography, and the reaction can be enlarged to grams scale.