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目的了解2008-2009年三门峡市克山病病情及发病趋势。方法 2008-2009年分别选灵宝市朱阳镇、卢氏县沙河乡为监测点。对监测点居民进行临床查体和心电图描记;对可疑克山病患者、可疑心脏增大者和心电图异常者拍摄胸部正位X线片,测量心胸比。采集监测点居民发样及其家中粮食(面粉)样品。用氢化物原子荧光光谱法进行含硒量检测。结果 2008-2009年三门峡市共检查1 529人,检出慢型克山病10例、潜在型克山病病例35例,检出率分别为0.63%(10/1 592)、2.20%(35/1 592)。共描记心电图1 592份,心电图异常274例,异常率为17.21%;异常心电图以ST-T改变[占17.88%(49/274)]、左心室高电压[占8.76%(24/274)],左室肥厚[占12.41%(34/274)]为主。采集粮食样品32份,粮硒平均为0.038 mg/kg;采集发硒样品30份,发硒中位数为0.285 mg/kg。结论三门峡市克山病病情呈平稳低发态势,但病区异常心电图比率较高,应积极开展防治研究。
Objective To understand the disease status and trend of Keshan disease in Sanmenxia City from 2008 to 2009. Methods From 2008 to 2009, we selected Zhuyang town of Lingbao city and Shahe town of Lushi county as monitoring points. Residents of the monitoring point for physical examination and electrocardiogram tracings; suspected Keshan disease, suspicious heart enlargement and ECG abnormalities were taken chest X-ray film, measurement of cardiothoracic ratio. Collect sample of residents and sample of grain (flour) at their monitoring points. Determination of selenium content by hydride atomic fluorescence spectrometry. Results A total of 1 529 people were examined in Sanmenxia from 2008 to 2009, 10 cases of chronic Keshan disease and 35 cases of potential Keshan disease were detected. The detection rates were 0.63% (10/1 592) and 2.20% (35) respectively / 1 592). A total of 1 592 electrocardiogram (ECG) and 274 abnormal electrocardiogram (ECG) abnormality rate was 17.21%. The abnormal electrocardiogram was changed by ST-T [17.88% (49/274)] and left ventricular high voltage [8.76% (24/274] , Left ventricular hypertrophy [12.41% (34/274]] based. 32 food samples were collected, the average grain selenium was 0.038 mg / kg; 30 selenium samples were collected and the median selenium concentration was 0.285 mg / kg. Conclusions The situation of Keshan disease in Sanmenxia City showed a steady and low tendency, but the rate of abnormal electrocardiogram in Ward was higher. Therefore, prevention and treatment should be actively carried out.