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目的探讨颅内血管外皮细胞瘤的诊断治疗方法。方法回顾性分析自1993年1月至2004年6月华山医院神经外科收治的63例颅内血管外皮细胞瘤的临床表现、影像学表现、病理检查及治疗。结果63例患者中58例获得肿瘤全切除,5例行次全切除。手术后56例症状好转或不变,6例症状有所加重,1例术后死于并发症。术后获得随访38例,其中34例接受放射治疗,随访期为3~84个月,平均25个月。30例恢复良好,2例有远处转移(至腰骶椎),6例肿瘤复发(均行再次手术,3例恢复尚可,2例有所加重,1例死于术后颅内感染等并发症)。结论颅内血管外皮细胞瘤是一类血供丰富的肿瘤,虽然生长较慢但是具有复发及转移的性质,因此手术应彻底切除肿瘤,术中应准备充足的血源,术前行部分供血动脉的栓塞对于减少术中出血、更安全地切除肿瘤有所帮助,同时辅以术后放射治疗以延缓复发,延长患者的生存期。
Objective To investigate the diagnosis and treatment of intracranial hemangiopericytoma. Methods The clinical manifestations, imaging findings, pathological examination and treatment of 63 patients with intracranial hemangiopericytoma admitted to Department of Neurosurgery, Huashan Hospital from January 1993 to June 2004 were retrospectively analyzed. Results Of the 63 patients, 58 had complete tumor resection and 5 had subtotal resection. 56 cases improved or unchanged after surgery, 6 cases had aggravated symptoms, 1 case died of complications after surgery. Thirty-eight patients were followed up, of which 34 patients underwent radiotherapy. The follow-up period ranged from 3 to 84 months with an average of 25 months. 30 cases recovered well, 2 cases had distant metastasis (to lumbosacral vertebra), 6 cases had tumor recurrence (all underwent reoperation, 3 cases recovered, 2 cases aggravated, 1 case died of postoperative intracranial infection, etc.) complication). Conclusions Intracranial hemangiopericytoma is a type of tumor rich in blood supply. Although it grows slowly but has the characteristics of recurrence and metastasis, the tumor should be completely resected during operation. Adequate blood supply should be provided during surgery. Partial preoperative arterial feeding Of the embolization for reducing intraoperative bleeding, safer removal of the tumor helpful, supplemented by postoperative radiotherapy to delay recurrence and prolong survival of patients.