作者评价了法国两个移植中心儿童异基因BMT的长期副作用。本组病例须符合下列标准:①在急性粒细胞白血病(AML)或急性淋巴细胞白血病(ALL)首次缓解后BMT,②白血病诊断至BMT时间短于6个月。 23例儿童在两个移植中心进行异基因BMT,其中13例符合上述标准(AML9例,ALL4例)。移植前均未接受颅脑照射。诊断至BMT中位时间为3月(2～6月),移植时年龄1～16岁(中位9岁)。BMT预处理方 The authors evaluated the long-term side effects of allogeneic BMT in children from two transplant centers in France. The group of patients to meet the following criteria: ① acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) after the first relief of BMT, ② leukemia diagnosis to BMT less than 6 months. Twenty-three children underwent allogeneic BMT in two transplant centers, 13 of whom met the above criteria (9 AML cases and 4 ALL). Have not received brain irradiation before transplantation. The median time to diagnosis of BMT was March (from February to June), and the age at transplantation was from 1 to 16 years (median 9 years). BMT preconditioner