A 19-year-old Asian Indian female presented with productive cough since the past one month and low grade fever since the pasl two weeks.She was diagnosed with pulmonary tuberculosis and treated with anlilubercular drugs.Subsequently,delayed cultures of bronclioalveolar lavage fluid grew Burkholderia pseudomallei(B.pseudomallei).On follow up the patient reported significant subjective improvement and ESR progressively returned to normal.In summary’,this case report raises two distinct and equally intriguing roles for B.pseudomallei,i.e.respiratory colonization and spontaneously resolving pulmonary infection.The pathogenic potential of B.pseudomallei,the eliologic agent of melioidosis,is well known.Confirmation of eilher colonization or spontaneous resolution,would potentially spare many patients unnecessary and oxpensivo therapy with broad-spectruin antibiotics,and contribute to more rational usage of antibiotics,especially in co-infecliou with Mycobacterium tuberculosis and B.pseudomallei-two bacterial diseases with closely similar clinical,radiologic and histopathologic features. A 19-year-old Asian Indian female presented with productive cough since the past one month and low grade fever since the pasl two weeks. He was diagnosed with pulmonary tuberculosis and treated with an ililubercular drugs.Subsequently, delayed cultures of bronclioalveolar lavage fluid grew Burkholderia Pseudomallei (B. pseudomallei) .On follow up the patient reported significant subjective improvement and ESR progressively returned to normal. summary ’, this case report raises two distinct and equally intriguing roles for B. pseudomallei, ierespiratory colonization and spontaneously resolving pulmonary infection The pathogenic potential of B. pseudomallei, the eliologic agent of melioidosis, is well known. Confirmation of eilher colonization or spontaneous resolution, would potentially spare many patients unnecessary and oxpensivo therapy with broad-spectruin antibiotics, and contribute to more rational usage of antibiotics , especially in co-infecliou with Mycobacterium tuberculosis and B. pseudomal lei-two bacterial diseases with closely similar clinical, radiologic and histopathologic features.