作者已经描述过 T 细胞和巨噬细胞相互作用的数学模式。在作者的模式中,有两种不同类型的细胞毒性效应细胞消除瘤细胞,即细胞毒 T 淋巴细胞(CTL)和细胞毒巨噬细胞。CTL 依据对存在于有活力的瘤细胞表面的抗原决定簇的识别而产生。细胞毒巨噬细胞的产生,由于受到辅助 T 细胞衍生的淋巴因子的激 The authors have described the mathematical model of T-cell and macrophage interactions. In the authors’ paradigm, two different types of cytotoxic effector cells eliminate tumor cells, cytotoxic T lymphocytes (CTLs) and cytotoxic macrophages. CTLs are based on the recognition of antigenic determinants present on the surface of viable tumor cells. The production of cytotoxic macrophages is stimulated by lymphokines derived from helper T cells