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本文通过聚乙二醇化的聚乙烯亚胺与壳聚糖反应,得到了水溶性良好的聚乙二醇化聚乙烯亚胺接枝的壳聚糖(mP EG-O-CS-PEI)。研究表明,纳米mP EG-O-CS-PEI对细胞SMMC7721的转染效率为7.1%。
In this paper, polyethylene glycolized polyethyleneimine grafted chitosan (mPEG-O-CS-PEI) was obtained by reacting pegylated polyethyleneimine with chitosan. The results showed that the transfection efficiency of nano-mP EG-O-CS-PEI to SMMC7721 cells was 7.1%.