病儿,女,日龄1d。生后1h面部发黄。系第5胎第4产,足月水囊引产。生后Apgar评分8分。出生时脐血胆红素95.76μmol/L,网织红0.89.生后即给吸氧,补液,鲁米那钠治疗。4h后发现患儿面部及皮肤有轻度黄染,并呈进行性加重。家族中其父血型BRh(+),体健,母亲血型BRh(-),患有先天性耳聋,并指,左前臂短,左手通贯掌等多发畸形。外祖父母血型均为Rh(+)。前4胎死于早产,重症溶血,严重黄疸。孕母检查羊水发现母儿Rh血型不合,妊娠36周给予宫内疗法。查体:足月 Sick child, female, age 1d. 1h after birth facial yellow. Department of the fourth birth of the fourth tire, full-term water bag induced labor. Apgar score of 8 points after birth. Born umbilical cord blood bilirubin 95.76μmol / L, reticulocyte 0.89 after birth to give oxygen, rehydration, luminal sodium treatment. 4h found that children with mild facial and skin yellow dye, and was progressive increase. Family of his father BRh (+), body health, mother blood type BRh (-), suffering from congenital deafness, and refers to the left forearm short, left hand through the palm and other multiple deformities. Both grandparents’ blood type is Rh (+). The first 4 died of premature birth, severe hemolysis, severe jaundice. Pregnant mother check the amniotic fluid found that the mother and child Rh blood group incompatibility, give intrauterine therapy 36 weeks gestation. Physical examination: full-term