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用缓释投递系统对疫苗剂型进行改造是目前ＷＨＯ和ＰＶＤ等国际卫生组织非常关注的课题之一，而以ＰＬＰＧ作为疫苗缓释投递材料又是近年来国外研究最多、应用最广、被认为最有前途的疫苗投递系统，本文主要从ＰＬＰＧ的化学合成与代谢、ＰＬＰＧ微颗粒的制备方法、ＰＬＰＧ微颗粒增强免疫应答的机理及在人体使用的安全性等方面作了介绍。
It is one of the topics that the WHO and PVD are very concerned about now that the vaccine dosage form is modified with the slow delivery delivery system. The PLPG as the vaccine delivery release material has been the most widely researched and widely used abroad in recent years. Promising vaccine delivery system, this article mainly from the chemical synthesis and metabolism of PLPG, preparation of PLPG microparticles, PLPG microparticles enhance the immune response mechanism and safety in human use were introduced.