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目的 探讨眼压与非对称性糖尿病视网膜病变颈部及球后血管血流动力学之间的相互关系。方法 ① 12例患者 (内分泌科诊断为 2型糖尿病 ;无高血压、心脑血管病及血液病等全身病 ;结合直接检眼镜和眼底荧光血管造影诊断为非对称性糖尿病视网膜病变 ) ,每位患者较重眼归为一组 ,较轻眼归为一组 ,共两组。②采用日本产TOPCON自动眼压仪测量眼压 ;采用美国产HDL -5 0 0 0型彩色多普勒仪检测患者颈部及球后血管血流动力学变化。③统计学处理 (SPSS10 0版统计软件 ) :两组眼压采用配对t检验 ;眼压与同侧血管血流动力学参数做相关分析。结果 ①较轻组眼压为 16 5 8± 1 5 1mmHg ,较重眼组为 18 42± 1 62mmHg ,两者相比有统计学差异 (P <0 0 1) ;②颈内动脉(ICA) :较轻组ICA收缩期峰值血流速度 (PSV )为 47 47± 8 62cm/s ,与眼压无相关性 (r =-0 160 ,P =0 619) ;较重组PSV为 43 63± 9 16cm /s ,与眼压无相关性 (r =-0 5 2 9,P =0 0 77)。③眼动脉 (OA) :较轻组PSV为 2 7 2 7± 12 2 0cm/s ,与眼压呈负相关 (r =-0 60 0 ,P =0 0 3 9) ;较重组PSV为 2 0 0 2± 5 3 2cm/s ,与眼压呈负相关 (r =-0 72 1,P =0 0 0 8)。④视网膜中央动脉(CRA) :较轻组PSV为 8 41± 2 0 5cm /s ,与眼压呈负相关 (r =
Objective To investigate the relationship between intracranial pressure and asymmetry of diabetic retinopathy and hemodynamics after the ball. Methods ① Twelve patients (type 2 diabetes diagnosed by Department of Endocrinology; systemic disease without hypertension, cardio-cerebrovascular disease and hematological disease; astigmatic diabetic retinopathy diagnosed by direct ophthalmoscopy and fundus fluorescein angiography), each Patients with heavier eyes grouped under a group of more light eyes, a total of two groups. (2) The intraocular pressure (IOP) was measured with TOPCON automatic tonometer in Japan. The HDL-5000 color Doppler was used to detect the hemodynamics of the neck and the posterior hemisphere. ③Statistical analysis (SPSS10 0 statistical software): Two groups of intraocular pressure using paired t test; IOP and ipsilateral vascular hemodynamic parameters do correlation analysis. Results ① In the mild group, the intraocular pressure was 16 5 8 ± 151 mmHg, in the severe eye group was 18 42 ± 1 62 mmHg, there was a significant difference between the two groups (P 0 01). The internal carotid artery (ICA) (P <0.05). The ICV peak systolic blood flow velocity (PSV) in the mild group was 47 47 ± 8 62 cm / s and no correlation with intraocular pressure (r = -0 160, P = 0 619) 16cm / s, no correlation with intraocular pressure (r = -0 5 2 9, P = 0 0 77). (3) Compared with the intraocular pressure, PSV in the mild group was 27 72 ± 12 20 cm / s, and negatively correlated with intraocular pressure (r = -0 60 0, P = 0 0 39) 0 0 2 ± 5 3 2cm / s, and negative correlation with intraocular pressure (r = -0 72 1, P = 0 0 0 8). Central retinal artery (CRA): The PSV of the mild group was 8 41 ± 20 05 cm / s, which was negatively correlated with intraocular pressure (r =