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慢性粒细胞性白血病(简称慢粒)是我国较为常见的白血病类型之一,约有58～80％的慢粒病例以慢粒急性变(简称慢粒急变)的形式进入疾病的终末期。慢粒急变后的治疗效果一般较差,病程进展快,常六个月内(平均二个月)死亡。努力提高慢粒急变的疗效对延长慢粒患者的生存期意义重大。目前已知慢粒急变后的细胞形态可表现为多样性,可为原粒细胞,也可主要为早幼粒、粒单型细胞、单核细胞或淋巴细胞型,甚至是
Chronic myelogenous leukemia (CML) is one of the more common types of leukemia in our country. About 58-80% of CML cases enter the terminal stage of the disease in the form of acute CML (abbreviated CML). CML after the general treatment effect is poor, fast course of progress, often six months (average two months) died. Efforts to improve the efficacy of chronic myogenic acute lengthening the survival of patients with chronic disease is of great significance. It is known that the morphological changes of cells after acute myasthenia grading can be as diverse as that of myeloblasts, mainly of promyelocytic, monocytic, monocytic or lymphoid types, and even