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目的探讨门体静脉分流术患者应用甘露聚糖肽对预防手术感染并发症的作用,为临床治疗提供参考依据。方法从医院2013年1月-2014年1月收治的行门体静脉分流术患者中随机选择100例进行研究,将其分为观察组和对照组,各50例,分别给予生理盐水和同剂量甘露聚糖肽静脉滴注,观察两组患者手术感染并发症情况,数据采用SPSS 15.0软件进行统计分析。结果术后4、7d,观察组的治疗总有效率分别为86.0%和90.0%,对照组分别为82.0%和84.0%,观察组高于对照组,但经比较差异无统计学意义;两组患者术后并发症发生率分别为6.0%和10.0%,经比较差异无统计学意义;但观察组的术后住院时间为(16.25±3.15)d,显著短于对照组的(19.03±3.95)d,差异有统计学意义(P<0.05)。结论门体静脉分流术患者应用甘露聚糖肽进行静脉滴注,可以有效预防手术感染并发症,效果显著。
Objective To investigate the role of mannan peptide in the prevention of complications of surgical infection in portal vein shunt patients and provide reference for clinical treatment. Methods A total of 100 patients were selected randomly from the hospital from January 2013 to January 2014 and were divided into observation group and control group, 50 cases in each group. They were given normal saline and the same dose Mannan peptide intravenous infusion, observation of complications in patients with surgical infection in two groups, the data using SPSS 15.0 software for statistical analysis. Results At 4 and 7 days after operation, the total effective rates in the observation group were 86.0% and 90.0% respectively, while those in the control group were 82.0% and 84.0% respectively. The observation group was higher than the control group, but the difference was not statistically significant. The incidence of postoperative complications was 6.0% and 10.0% respectively, but the difference was not statistically significant. However, the postoperative hospital stay in observation group was (16.25 ± 3.15) d, which was significantly shorter than that in control group (19.03 ± 3.95) d, the difference was statistically significant (P <0.05). Conclusion Intravenous instillation of mannan peptide in patients with portal vein shunt can effectively prevent the complications of surgical infection, and the effect is remarkable.