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心房颤动的发生和维持与缝隙连接蛋白密切相关。近年来发现心房颤动的伴随症状如心房纤维化、心房扩大、炎症以及遗传因素均可独立于心房颤动之外使缝隙连接蛋白发生改变,从而促进心房颤动的发生与维持。对心房颤动伴随症状的治疗有望成为心房颤动治疗的新靶点。
The occurrence and maintenance of atrial fibrillation is closely related to connexin. In recent years, found that accompanying symptoms of atrial fibrillation such as atrial fibrosis, atrial enlargement, inflammation and genetic factors can be independent of atrial fibrillation outside of the gap junction protein changes, thereby promoting the occurrence and maintenance of atrial fibrillation. The treatment of atrial fibrillation associated symptoms is expected to become a new target for the treatment of atrial fibrillation.